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Coenzyme Q10 supplements and arthritis

This paper by Bauerova and colleagues looks into the Effect of coenzyme Q(10) supplementation in the rat model of adjuvant arthritis.
The Group is based at the Institute of Experimental Physiology in Bratislava.
They state that Adjuvant arthritis (AA) is a model of chronic inflammation and that it is induced by Mycobacterium butyricum, furthermore it is characterised by similar pathophysiological and pathobiochemical changes as rheumatoid arthritis (RA) in humans.

They tested to see if supplemental coenzyme Q10 is capable of suppressing inflamation of the hind paw and the effect upon body weight in animals that suffered from the arthritis condition. They found that despite ‘the unfavorable effects on the rheumatic processes observed by monitoring biometric parameters (hind paw volume, relative body weight, relative weight of spleen), a significant protective effect was observed on the level of mitochondrial energetic and antioxidant disbalance’.

This strongly suggests that coenzyme Q10 took as a supplement may be useful for arthritis sufferers, especially if used as part of a combinatory therapy.

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