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Future of tissue engineering in rheumatic diseases.


This article looking into the connection between joint repair and rheumatic diseases is by Ringe and colleagues from Berlin. It is available in full from pubmed using the ID 17309320.
Chronic inflammation during rheumatoid arthritis and degenerative processes during osteoarthritis eventually result in joint destruction.
Anti-inflammatory therapies facilitate the inhibition or delay of progressing joint cartilage and bone loss, but do not regenerate these tissues. Surgical procedures are quite unsatisfactory in long-term evaluation and often lead to endoprothetic joint replacement. Present tissue engineering technologies offer new strategies for the treatment of cartilage and bone defects. Here, beyond implantation of cell suspensions, biomaterials combined with tissue-specific cells or mesenchymal stem cells are clinically applied. This review focuses on state-of-the-art and future in situ mesenchymal stem cell-based tissue engineering approaches for joint repair in patients with rheumatic diseases.
The full article is published in the journal expert opinion on biological therapy.

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1 Comment

  1. Hi,

    My name is Jenny and I am part of an online community called CarePlace, for people experiencing similar health related issues and their caregivers, including Rheumatoid Arthritis. We have recently added new Rheumatoid Arthritis related communities to the site.

    As your blog relates to what we are doing at CarePlace, I was wondering if you might be willing to check out our site and let me know if you think it might be helpful to the people who communicate through and with you. People can join multiple communities, share experiences, check out info on medical conditions and treatments and form their own groups within the site.

    We have gotten great feedback and as you know the more people in various communities the more outreach and support that happens. Our users have really liked it so far and we are adding new features all the time based on what everyone is telling us.

    It’s really important to us to get feedback from people like you about the site as we develop features – the site is www.careplace.com. You can add me as a friend (jend) and let me know what you think.

    Thanks in advance!

    Jenny (jend)

    Comment by Jenny Desmond — February 23, 2007 @ 2:57 pm

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