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Posted in Uncategorized February 7th, 2007 by admin | No comments
This article by D Booth et al from the university of Birmingham takes a look at the links between obesity and arthritis.
Diverse customary patterns of eating, drinking or movement are hypothesised to be effective in weight control based on laboratory experiments or theoretical calculations, in some cases supported by ecologically valid evidence. This method is applicable to healthy members of the public and to patients at high risk of and from obesity such as those having type-2 diabetes or chronic arthritis. Weight-reducing behaviour not adequately identified in current best practice educational messages includes: integration of exercise into desk-based employment; uses of stairs; uncompensated vigorous activity or reduction in amount eaten at a meal; protein level and carbohydrate timing in meals; having a “snack”. This paper presents the scientific parts of a request for funds to integrate a suite of research methods based on theoretical models that can be applied to identify further, culturally and locally specific eating customs that avoid overweight and reduce obesity and can be iterated in a continuous (re)development of evidence-based expert advice and self-care practices in health and chronic disease.
The pubmed identifier for this article is 17055110
Posted in Small scale experiments February 7th, 2007 by admin | No comments
This abstract linking arthritis and breast cancer is by Candelaria et al from the department of Hematologia in Mexico.
BACKGROUND: Estrogen plays a critical role in breast cancer. Thereafter, endocrine therapy is a standard of care in patients with breast carcinoma, expressing ER or PR.
CASE PRESENTATION: Herein we report the case of a 53-year old patient, who developed cholestasis and vasculitis during the treatment with tamoxifen. This toxicity was reversable after the removal of the drug. Thereafter she continued adjuvant treatment for breast carcinoma with anastrazole. Since tamoxifen has been widely indicated for patients with breast carcinoma, we did a literature review, looking for other cases with this type of toxicity.
CONCLUSION: This case is the third with vasculitis informed in the literature, but the first one that additionally developed cholestasis and arthritis. Although it is rare, we discuss the indication of this drug in the actual era, where aromatase inhibitors offer a better security profile.
Pubmed ID is 17244373
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Posted in Patient trials, Uncategorized February 1st, 2007 by admin | No comments
