All the latest news on Arthritis research

Future of tissue engineering in rheumatic diseases.


This article looking into the connection between joint repair and rheumatic diseases is by Ringe and colleagues from Berlin. It is available in full from pubmed using the ID 17309320.
Chronic inflammation during rheumatoid arthritis and degenerative processes during osteoarthritis eventually result in joint destruction.
Anti-inflammatory therapies facilitate the inhibition or delay of progressing joint cartilage and bone loss, but do not regenerate these tissues. Surgical procedures are quite unsatisfactory in long-term evaluation and often lead to endoprothetic joint replacement. Present tissue engineering technologies offer new strategies for the treatment of cartilage and bone defects. Here, beyond implantation of cell suspensions, biomaterials combined with tissue-specific cells or mesenchymal stem cells are clinically applied. This review focuses on state-of-the-art and future in situ mesenchymal stem cell-based tissue engineering approaches for joint repair in patients with rheumatic diseases.
The full article is published in the journal expert opinion on biological therapy.

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Creatine supplementation improves muscular performance in older men.


It has long been known that creatine supplementation can enhance muscle strength and power after only five to seven days in young adults. But did you know that they are also able to benefit older individuals where aging is associated with a decrease in muscle strength and explosive power?
In a study by Gotshalk and colleagues that is published in the journal ‘Medicine and Science in Sports and Exercises (Pumbed ID 11880821) it was found that seven days of creatine supplements in normally active older men (between the ages of fifty nine to seventy two) that seven days of creatine supplementation is effective at increasing several indices of muscle performance, including functional tests in older men without adverse side effects. There are many places where you can buy discount creatine supplements nowadays and these supplements may prove to be a very useful herapeutic strategy for older adults in their fight against muscle loss.

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Avoidance of unhealthy fattening.


This recent paper by Booth and colleagues at the university of Birmingham in Englans takes a look at eating patterns intodays society and analyses the long term effects of weight control with diseases such as Arthritis.

Diverse customary patterns of eating, drinking or movement are hypothesised to be effective in weight control based on laboratory experiments or theoretical calculations, in some cases supported by ecologically valid evidence.
This method is applicable to healthy members of the public and to patients at high risk of and from obesity such as those having type-2 diabetes or chronic arthritis. Weight-reducing behaviour not adequately identified in current best practice educational messages includes: integration of exercise into desk-based employment; uses of stairs; uncompensated vigorous activity or reduction in amount eaten at a meal; protein level and carbohydrate timing in meals; having a “snack”.
This paper presents the scientific parts of a request for funds to integrate a suite of research methods based on theoretical models that can be applied to identify further, culturally and locally specific eating customs that avoid overweight and reduce obesity and can be iterated in a continuous (re)development of evidence-based expert advice and self-care practices in health and chronic disease.

The full article is available via pubmed by using the id 17055110

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